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遗传性皮肤病

Genodermatoses.

作者信息

Schulz E J

机构信息

Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa.

出版信息

Dermatol Clin. 1994 Oct;12(4):787-96.

PMID:7805308
Abstract

This article describes some of the genodermatoses encountered in the black populations in Africa, starting with ainhum, which appears to be genetically determined. Palmoplantar keratodermas are common in Africa but are difficult to classify and their hereditary nature is not always recognized. Of the ichthyoses, the lamellar type is commonest, with the so-called bathing-suit distribution apparently unique to Africans. Albinism and xeroderma pigmentosum are important causes of cutaneous malignancy in the tropics. Neurofibromatosis and tuberous sclerosis are relatively common, whereas hypermelanosis of Ito is rare but easy to recognize in dark skin.

摘要

本文介绍了在非洲黑人人群中遇到的一些遗传性皮肤病,首先是似乎由基因决定的断肢症。掌跖角化病在非洲很常见,但难以分类,其遗传性质也并非总能被认识到。在鱼鳞病中,板层状鱼鳞病最为常见,所谓的泳衣样分布显然是非洲人所特有的。白化病和着色性干皮病是热带地区皮肤恶性肿瘤的重要病因。神经纤维瘤病和结节性硬化症相对常见,而伊藤色素沉着增多症很少见,但在深色皮肤中很容易识别。

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