Hancock E B, Newell D H
Department of Periodontics, Indiana University School of Dentistry, Indianapolis.
Dent Clin North Am. 1994 Oct;38(4):719-31.
Antimicrobial agents provide an additional means of combating the infective agents encountered in the periodontal diseases. Delivery methods include oral rinses, dentifrices, irrigation, local delivery, and systemic administration. Agents and delivery methods should be selected with the following criteria in mind: 1. The agent must be effective against the organisms present. 2. The agent must reach the desired site of action in appropriate concentration. 3. The agent must remain at the site for a sufficient period of time. When combined with a careful patient assessment and a considered diagnosis, the use of antimicrobial agents may prove to be an important adjunct in total periodontal therapy.
抗菌剂为对抗牙周疾病中遇到的感染因子提供了一种额外的手段。给药方法包括口腔冲洗、牙膏、冲洗、局部给药和全身给药。选择药物和给药方法时应考虑以下标准：1. 该药物必须对存在的微生物有效。2. 该药物必须以适当的浓度到达期望的作用部位。3. 该药物必须在该部位停留足够长的时间。当与仔细的患者评估和深思熟虑的诊断相结合时，抗菌剂的使用可能被证明是全面牙周治疗中的一项重要辅助手段。
