Amital H, Shoenfeld Y
Dept. of Medicine B, Chaim Sheba Medical Center, Tel Hashomer.
Harefuah. 1994 Dec 1;127(11):448-50, 503.
Thrombocytopenia following heparin treatment appears in 5% of patients so treated. In 20% of such patients paradoxical thromboembolic phenomena may be associated with the thrombocytopenia. This process is most probably mediated via an antibody reaction against a heparin-platelet complex. We present a 70-year-old woman with recurrent episodes of lower extremity thrombophlebitis associated with thrombocytopenia following treatment with heparin for pulmonary embolism.
接受肝素治疗的患者中，5%会出现血小板减少症。在这些患者中，20%可能会出现与血小板减少症相关的反常血栓栓塞现象。这个过程很可能是通过针对肝素-血小板复合物的抗体反应介导的。我们报告了一位70岁女性，她在因肺栓塞接受肝素治疗后，反复出现下肢血栓性静脉炎并伴有血小板减少症。
