Coadministration of fluvoxamine increases serum concentrations of haloperidol.
作者信息
Daniel D G, Randolph C, Jaskiw G, Handel S, Williams T, Abi-Dargham A, Shoaf S, Egan M, Elkashef A, Liboff S
机构信息
Clinical Brain Disorders Branch, NIMH Neuroscience Center at Saint Elizabeths, Washington, D.C.
出版信息
J Clin Psychopharmacol. 1994 Oct;14(5):340-3.
PMID:7806690
Abstract
Four patients with chronic schizophrenia were treated with a combination of fluvoxamine, haloperidol, and benztropine. The combination significantly impaired performance on tests of delayed recall memory and attentional function. Haloperidol concentrations in serum were monitored in three patients and were robustly elevated by fluvoxamine.
摘要
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