Ciesielski S D
Family Practice Residency Program, Natividad Medical Center, Salinas, California 93906.
J Fam Pract. 1995 Jan;40(1):76-80.
The resurgence in tuberculosis necessitates careful surveillance and sensitive detection of cases. The purified protein derivative (PPD) test is the foundation of tuberculosis control. Primary care clinicans are encountering increasing numbers of persons immigrating from countries in which BCG (bacille Calmette-Guérin) vaccination is common. Many health care providers believe that previous BCG vaccination usually results in a positive PPD test, and therefore consider BCG vaccination status when interpreting a positive result on the PPD test. All articles listed in MEDLINE that included BCG and PPD as key words, a total of 62, were reviewed. Articles published before computerization of the medical literature, a total of 35, were reviewed in Index Medicus. This literature review indicates that there is little relationship between BCG vaccination and PPD positivity, and that BCG vaccination status should not be considered in the interpretation of a positive PPD test.
结核病的再度流行使得对病例进行仔细监测和灵敏检测成为必要。结核菌素纯蛋白衍生物（PPD）试验是结核病防控的基础。基层医疗临床医生遇到越来越多来自普遍接种卡介苗（BCG，即卡介菌）国家的移民。许多医疗服务提供者认为，先前接种卡介苗通常会导致PPD试验呈阳性，因此在解读PPD试验阳性结果时会考虑卡介苗接种状况。对MEDLINE中列出的所有以卡介苗和PPD作为关键词的文章（共62篇）进行了综述。对医学文献计算机化之前发表的文章（共35篇）在《医学索引》中进行了综述。这篇文献综述表明，卡介苗接种与PPD阳性之间几乎没有关联，并且在解读PPD试验阳性结果时不应考虑卡介苗接种状况。
