Leguire L E, Suh S, Rogers G L, Bremer D L
Department of Ophthalmology, Columbus Children's Hospital, OH 43205.
J Pediatr Ophthalmol Strabismus. 1994 Jul-Aug;31(4):256-61. doi: 10.3928/0191-3913-19940701-13.
Two experiments were undertaken to assess high contrast-high luminance (HCHL) and low contrast-low luminance (LCLL) visual acuity as measured with the Smith-Kettlewell Institute Low Luminance (SKILL) card, in childhood amblyopia. In experiment 1, HCHL and LCLL visual acuity was measured in 11 amblyopic children and in 12 normal children of similar age. The results revealed that HCHL visual acuity was similar in the normal eyes and in the amblyopes' dominant eyes, and was abnormal in 91% of the amblyopic eyes. LCLL visual acuity was significantly worse in normal eyes compared to the amblyopes' dominant eyes, and was abnormal in only 64% of the amblyopic eyes. In experiment 2, HCHL and LCLL visual acuity was measured in seven previously tested amblyopic children, after a 5-month interval, and in six additional amblyopic children. In the amblyopic children who were tested twice, significant test-retest reliability for HCHL and LCLL visual acuity was found and visual acuity varied by 3.6%. The results of experiment 2 corroborated the results of experiment 1 from the amblyopic children. It is concluded that visual acuity in the amblyopic eye tends to normalize under low contrast-low luminance conditions. In addition, the mechanism(s) underlying amblyopia appear also to influence the dominant eye, resulting in superior visual acuity under low contrast-low luminance conditions.
进行了两项实验，以评估使用史密斯-凯特尔韦尔眼科学会低亮度（SKILL）视力表测量的高对比度-高亮度（HCHL）和低对比度-低亮度（LCLL）视力，研究对象为儿童弱视患者。在实验1中，对11名弱视儿童和12名年龄相仿的正常儿童测量了HCHL和LCLL视力。结果显示，正常眼和弱视眼的优势眼的HCHL视力相似，91%的弱视眼的HCHL视力异常。与弱视眼的优势眼相比，正常眼的LCLL视力明显更差，仅64%的弱视眼的LCLL视力异常。在实验2中，对7名先前已测试过的弱视儿童在间隔5个月后再次测量了HCHL和LCLL视力，并对另外6名弱视儿童进行了测量。在接受两次测试的弱视儿童中，发现HCHL和LCLL视力具有显著的重测信度，视力变化为3.6%。实验2的结果证实了实验1中弱视儿童的结果。研究得出结论，弱视眼的视力在低对比度-低亮度条件下倾向于正常化。此外，弱视的潜在机制似乎也会影响优势眼，导致在低对比度-低亮度条件下视力更好。
