Saito A
Department of Pharmacology, University of Tsukuba, Ibaraki, Japan.
Yakugaku Zasshi. 1994 Oct;114(10):765-74. doi: 10.1248/yakushi1947.114.10_765.
In addition to sympathetic vasoconstrictor nerves, nonadrenergic, noncholinergic vasodilator nerves control the vascular tone. In cerebral arteries of various species of animals, nitric oxide (NO) is a potential candidate for the vasodilator transmitter. In rat mesenteric arterioles, calcitonin gene-related peptide (CGRP) functions as a transmitter. In guinea pig mesenteric arteries, multiple transmitters including NO and CGRP mediate the vasodilator response. The physiological and pathophysiological significance of vasodilator nerves is to be determined.
除了交感缩血管神经外,非肾上腺素能、非胆碱能舒血管神经控制血管张力。在多种动物的脑动脉中,一氧化氮(NO)是舒血管递质的一个潜在候选者。在大鼠肠系膜小动脉中,降钙素基因相关肽(CGRP)发挥递质作用。在豚鼠肠系膜动脉中,包括NO和CGRP在内的多种递质介导舒血管反应。舒血管神经的生理和病理生理意义有待确定。