Braun E M, Kikot' V A, Iugrinov O G, Sorokin B V
Klin Khir (1962). 1994(5):6-9.
The treatment experience of 127 patients with the locally spread rectal cancer was summarized. The combined with preoperative intraarterial chemotherapy course application causes significant injurious effect on the tumor (more than 3 times decrease of the viable tumor tissue part by volume in rectal adenocarcinoma, the appearance of subcapsular necrosis regions in metastatically injured regional lymphatic nodes in 32.2% of observations) and is characterized by low common toxicity.
总结了127例局部扩散直肠癌患者的治疗经验。术前动脉内化疗疗程的联合应用对肿瘤产生显著的损伤作用(直肠腺癌中存活肿瘤组织部分体积减少超过3倍,32.2%的观察病例中转移损伤的区域淋巴结出现包膜下坏死区域),且总体毒性较低。