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乳腺癌患者DNA流式细胞术及激素受体与腋窝淋巴结状态的相关性

Correlation of DNA flow cytometry and hormone receptors with axillary lymph node status in patients with carcinoma of the breast.

作者信息

Friedman N S, Freedman M D

机构信息

Sinai Hospital of Baltimore, MD.

出版信息

Md Med J. 1994 Nov;43(11):963-5.

PMID:7808198
Abstract

Axillary lymph node dissection (ALND) remains a standard staging procedure for patients with primary carcinoma of the breast. In a retrospective review of 63 patients with primary breast cancer who underwent ALND, statistical analysis showed that only tumor size was correlated with axillary lymph node involvement. Neither hormone receptor status, ploidy, nor percent S-phase contributed more to prediction of nodal size. Statistical analysis also indicated a significant correlation between receptor-negative status and the presence of positive axillary lymph nodes.

摘要

腋窝淋巴结清扫术(ALND)仍然是乳腺癌患者的标准分期程序。在一项对63例行ALND的原发性乳腺癌患者的回顾性研究中,统计分析表明,只有肿瘤大小与腋窝淋巴结受累相关。激素受体状态、倍体或S期百分比对淋巴结大小的预测作用均不明显。统计分析还表明,受体阴性状态与腋窝淋巴结阳性之间存在显著相关性。

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