Caione P, Nappo S, Capozza N, Minni B, Ferro F
Dipartimento di Chirurgia, Ospedale Pediatrico Bambino Gesù-Roma.
Minerva Pediatr. 1994 Oct;46(10):437-43.
Nowadays enuresis is a problem that pediatric urologists are often called to treat, since it affects 15 to 30% of school-age children. In 85% of affected children bedwetting is monosymptomatic, not accompanied by other voiding disorders or daytime incontinence. Treatment of choice is still highly controversial, as the physiopathology is not yet fully understood and the pathogenesis is multifactorial: genetic and psychological factors, sleep disorders, urinary reservoir abnormalities, urine production disorders can all play a part. Behavioural treatments (psychotherapy, bladder training and biofeedback, electric alarm) and pharmacological therapy (tricyclic antidepressants, anticholinergics, DDAVP) have been used with variable results. In our 1 year experience (54 enuretic children) DDAVP proved to be effective in reducing the number of wet nights per week in 79% of cases. Acupuncture, which we have been using for many years, also gave good results in 55% of treated patients. Long term success of DDAVP and acupuncture was respectively 50 and 40%. We discuss the probable pathophysiology and present our own results and those reported in the literature. It has to be stressed that an accurate diagnostic selection of patients and a better understanding of physiopathology are the basis of effective treatment of enuresis.
如今,遗尿症是小儿泌尿科医生经常需要治疗的问题,因为它影响着15%至30%的学龄儿童。在85%的患病儿童中,尿床是单一症状,不伴有其他排尿障碍或日间尿失禁。由于其生理病理学尚未完全明了且发病机制是多因素的(遗传和心理因素、睡眠障碍、储尿异常、尿液生成障碍都可能起作用),所以治疗方法的选择仍极具争议。行为治疗(心理治疗、膀胱训练和生物反馈、电子警报)和药物治疗(三环类抗抑郁药、抗胆碱能药物、去氨加压素)的效果各不相同。根据我们一年的经验(54名遗尿儿童),去氨加压素在79%的病例中被证明能有效减少每周尿床的次数。我们多年来一直在使用的针灸疗法,在55%的接受治疗的患者中也取得了良好效果。去氨加压素和针灸的长期成功率分别为50%和40%。我们讨论了可能的病理生理学,并展示了我们自己的结果以及文献中报道的结果。必须强调的是,对患者进行准确的诊断筛选以及更好地理解生理病理学是有效治疗遗尿症的基础。