Hebeda K M, Menovsky T, Beek J F, Wolbers J G, van Gemert M J
Laser Center, Academic Medical Center, Amsterdam, The Netherlands.
Neurosurgery. 1994 Oct;35(4):720-2; discussion 722-4. doi: 10.1227/00006123-199410000-00019.
In this study, the penetration of red laser light (632.8 nm) in fresh bovine brain was measured parallel, oblique, and perpendicular to the axis of white matter tracts. The measurements were performed in eight samples with an isotropic light source and detector and were obtained by advancing the detector tip toward the light source in the tissue. A statistically significant difference in the effective attenuation coefficient of the light (mueff) was found between the parallel and perpendicular directions, 0.47 +/- 0.06 mm -1 and 0.63 +/- 0.13 mm-1, respectively (P = 0.005). The measurements taken at an angle of 45 degrees in the same sample resulted in an intermediate mueff of 0.58 +/- 0.09 mm-1. These results suggest a preferential guidance of light along the axis of the white matter tracts of the brain.
在本研究中，测量了红色激光（632.8纳米）在新鲜牛脑中平行、倾斜和垂直于白质束轴的穿透情况。测量在八个样本中进行，使用各向同性光源和探测器，通过在组织中将探测器尖端向光源推进来获取数据。在平行和垂直方向之间发现光的有效衰减系数（mueff）存在统计学显著差异，分别为0.47±0.06毫米-1和0.63±0.13毫米-1（P = 0.005）。在同一样本中以45度角进行的测量得出中间的mueff为0.58±0.09毫米-1。这些结果表明光沿脑白质束轴存在优先导向。
