Zogno C, Berti E, Coci A, Schiaffino E
Servizio di Anatomia e Istologia Patologica, Ospedale S. Carlo Borromeo di Milano.
Pathologica. 1994 Jun;86(3):319-23.
Is a rare soft tissue benign tumor usually appearing during the first two years of life, often occurring in axillary or upper arm region subcutaneous tissue. Surgery is the treatment of choice. The lesion histologically consists of three different tissue elements: dense mature fibrocollagenous, loose immature myxoid mesenchymal and mature adipose tissue. A case of fibrous hamartoma of infancy with the usual clinical characteristics, but with particular microscopic features due to the abundance in fibrocollagenous and scarcity of myxoid tissue, is described. The results of the immunohistochemical and ultrastructural study on the same patient are reported. The differential diagnostic problems are discussed.
是一种罕见的软组织良性肿瘤，通常在出生后的头两年出现，常发生于腋窝或上臂区域的皮下组织。手术是首选的治疗方法。该病变在组织学上由三种不同的组织成分组成：致密成熟的纤维胶原组织、疏松未成熟的黏液样间充质组织和成熟的脂肪组织。本文描述了一例具有典型临床特征，但因纤维胶原组织丰富和黏液样组织稀少而具有特殊微观特征的婴儿纤维性错构瘤病例。报告了对同一患者进行免疫组织化学和超微结构研究的结果。并讨论了鉴别诊断问题。
