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经皮二尖瓣成形术与直视二尖瓣交界切开术:两种技术近期疗效比较

[Percutaneous mitral valvuloplasty and open mitral commissurotomy: comparison of 2 techniques in immediate results].

作者信息

Olmos A, Seguel I, Gajardo J, Ghyra A, Santander C, Alarcón E, Saldaña A, Piana M E, Palacios S, Lama A

机构信息

Seccione de Cardiología, Facultad de Medicina Universidad de Concepción, Chile.

出版信息

Rev Med Chil. 1994 Mar;122(3):274-82.

PMID:7809517
Abstract

The aim of this study was to assess the real usefulness of percutaneous mitral balloon valvuloplasty (PMV). Eighty patients aged less than 56 years old, with symptomatic pure mitral stenosis, with an hemodynamic and echocardiographic area < 1.5 cm2, without associated valvular or coronary lesions and without surgical contraindications were studied. These were randomized in two groups of similar age, sex, symptomatology, cardiac rhythm, severity of stenosis and valve anatomy, that were subjected to PMV (n = 38) using a double balloon technique or to mitral commissurotomy (n = 42) with extracorporeal circulation (MC). Mitral areas (calculated using modified Gorlin's formula) increased in 1.15 +/- 0.28 and 1.72 +/- 0.34 cm2 in patients subjected to PMV and MC respectively. No patient died, there was one technical failure with PMV and two patients subjected to MC had a surgical wound infection. Mitral regurgitation increased in more than one degree in two patients treated with PMV (5%) and in 6 patients treated with MC (15%). It is concluded that PMV and MC are highly effective and safe procedures for the treatment of mitral stenosis. Mitral areas obtained with MC are higher than with PMV, however a significant improvement of the disease is achieved with both procedures and MC produces mitral regurgitation with a higher frequency.

摘要

本研究的目的是评估经皮二尖瓣球囊成形术(PMV)的实际效用。研究对象为80例年龄小于56岁、有症状的单纯二尖瓣狭窄患者,其血流动力学和超声心动图显示瓣口面积<1.5平方厘米,无相关瓣膜或冠状动脉病变且无手术禁忌证。这些患者按年龄、性别、症状、心律、狭窄严重程度和瓣膜解剖结构随机分为两组,一组采用双球囊技术进行PMV(n = 38),另一组进行体外循环二尖瓣交界切开术(MC,n = 42)。接受PMV和MC的患者二尖瓣面积(使用改良戈林公式计算)分别增加了1.15±0.28平方厘米和1.72±0.34平方厘米。无患者死亡,PMV有1例技术失败,2例接受MC的患者出现手术伤口感染。接受PMV治疗的2例患者(5%)和接受MC治疗的6例患者(15%)二尖瓣反流程度增加超过1级。结论是,PMV和MC是治疗二尖瓣狭窄的高效且安全的手术。MC获得的二尖瓣面积高于PMV,然而两种手术都能使病情得到显著改善,且MC导致二尖瓣反流的频率更高。

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