伴有急性椎间盘脓肿的曲霉菌性椎间盘炎

Aspergillus discitis with acute disc abscess.

作者信息

Assaad W, Nuchikat P S, Cohen L, Esguerra J V, Whittier F C

机构信息

Department of Internal Medicine, Northeastern Ohio Universities College of Medicine, Canton.

出版信息

Spine (Phila Pa 1976). 1994 Oct 1;19(19):2226-9. doi: 10.1097/00007632-199410000-00019.

DOI:10.1097/00007632-199410000-00019

PMID:7809759

Abstract

STUDY DESIGN

Aspergillus osteomyelitis of the vertebral body and disc space is rare. This report discusses a case that occurred in an immunosuppressed 29-year-old man and reviews the pertinent medical literature.

OBJECTIVES

To review the management and treatment of Aspergillus osteomyelitis of the vertebral body and disc space.

SUMMARY OF BACKGROUND DATA

The patient presented with acute neurologic compromise resulting from L5-S1 discitis and a large epidural soft tissue component secondary to the Aspergillus infection.

RESULTS

The patient underwent aggressive surgical debridement along with treatment with amphotericin B and had a complete clinical recovery.

CONCLUSIONS

The authors recommend a combined medical-surgical approach in most cases of vertebral Aspergillus osteomyelitis. Early surgery with vigorous surgical debridement along with antifungal treatment seems to yield a good outcome.

摘要