Schwan H P
Bioengineering Department, University of Pennsylvania, Philadelphia 19104.
Ultrasound Med Biol. 1994;20(7):639-44. doi: 10.1016/0301-5629(94)90112-0.
We briefly review my early contacts with bioacoustics and the bioacoustic work at the University of Pennsylvania that took place from the early 1950s to 1975. It was carried out with E. L. Carstensen, K. Li, A. Smith, H. Pauly, J. Reid, P. Edmonds and many students. The emphasis was first on basic biophysical studies. The work with E. Carstensen and H. Pauly was primarily concerned with the mechanism causing the high absorption typical for tissues and cell suspensions. Macromolecular content was shown to be largely responsible for the absorption. Practical applications concerned the relative merits of electromagnetic and ultrasonic diathermy techniques. P. Edmonds extended the range of macromolecular studies to 100 MHz and initiated work on the attenuation in lung tissues. After J. Reid came to Pennsylvania, the development of echocardiography took place.
我们简要回顾一下我早期与生物声学的接触，以及20世纪50年代初至1975年在宾夕法尼亚大学开展的生物声学研究工作。这项工作是与E. L. 卡斯滕森、K. 李、A. 史密斯、H. 保利、J. 里德、P. 埃德蒙兹以及众多学生共同进行的。最初重点是基础生物物理学研究。与E. 卡斯滕森和H. 保利合作的工作主要关注导致组织和细胞悬液典型高吸收的机制。结果表明大分子含量在很大程度上造成了这种吸收。实际应用涉及电磁透热疗法和超声透热疗法的相对优点。P. 埃德蒙兹将大分子研究范围扩展到了100兆赫兹，并启动了肺部组织衰减方面的研究。J. 里德来到宾夕法尼亚大学后，超声心动图得到了发展。
