Suppr超能文献

[心肌梗死后冬眠心肌]

[Postinfarction hibernating myocardium].

作者信息

Montalescot G, Faraggi M, Drobinski G, Le Guludec D, Grosgogeat Y, Thomas D

机构信息

Service de cardiologie, hôpital Pitié-Salpêtrière, Paris.

出版信息

Arch Mal Coeur Vaiss. 1994 Jan;87(1):79-84.

PMID:7811155
Abstract

The detection of hibernating myocardium after infarction is important because it justifies the discussion concerning the revascularisation of infarcted zones irrigated by occluded or severely stenosed vessels, but with an adequate collateral circulation to allow hibernation. The detection of hibernating myocardium is particularly important in patients without the classical indications for revascularisation, such as residual spontaneous ischaemia or ischaemia provoked by exercise or pharmacological stress testing. All techniques currently in use tend to overestimate the size of the necrosed, fibrous scar, compared with the amount of viable myocardium. Improved regional myocardial function after revascularisation is the most convincing proof of hibernating myocardium but it can only be obtained retrospectively. The detection of a reserve of contractility in the necrosed territory by an inotropic stimulus is well adapted to the demonstration of stunned myocardium but this method has not been proved in hibernating myocardium. Thallium scintigraphy is certainly useful in the prospective diagnosis of hibernating myocardium but the protocol of examination should be adapted to this specific problem. There is little available data concerning the evaluation of hibernating myocardium by positron emission tomography: the technical advantages of this method in assessing myocardial viability should enable a more accurate evaluation of post-infarction hibernating myocardium. Adequate revascularisation of necrosed territories depends on a deeper understanding and more precise prospective assessment of postinfarction hibernating myocardium.

摘要

心肌梗死后冬眠心肌的检测很重要,因为这为关于闭塞或严重狭窄血管所灌注梗死区域的血运重建的讨论提供了依据,这些梗死区域虽有足够的侧支循环以维持心肌冬眠。在没有血运重建的典型指征(如残余的自发性缺血或运动或药物负荷试验诱发的缺血)的患者中,冬眠心肌的检测尤为重要。与存活心肌的量相比,目前使用的所有技术往往都会高估坏死、纤维瘢痕的大小。血运重建后局部心肌功能的改善是冬眠心肌最有说服力的证据,但这只能通过回顾性研究获得。通过正性肌力刺激检测坏死区域的收缩储备非常适合于检测顿抑心肌,但这种方法在冬眠心肌中尚未得到证实。铊闪烁扫描在冬眠心肌的前瞻性诊断中肯定是有用的,但检查方案应针对这一特定问题进行调整。关于正电子发射断层扫描评估冬眠心肌的可用数据很少:该方法在评估心肌活力方面的技术优势应能更准确地评估心肌梗死后的冬眠心肌。坏死区域的充分血运重建取决于对心肌梗死后冬眠心肌有更深入的理解和更精确的前瞻性评估。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验