Meert T F, Clincke G H
Department of Neuropsychopharmacology, Janssen Research Foundation, Beerse, Belgium.
Alcohol Alcohol. 1994 Sep;29(5):489-92.
A series of experiments was performed, which indicated that 7-OHDPAT is only active in rats that are still in the dynamic phase of the development of a high and stable level of alcohol preference and in a drug discrimination test procedure, but not in rats with a matured preference for 3% alcohol. These data may point to a limited use of 7-OHDPAT in conditions of alcohol misuse and dependence.
进行了一系列实验，结果表明7-羟基二苯丙氨酸仅在仍处于高且稳定的酒精偏好发展动态阶段的大鼠以及药物辨别试验程序中具有活性，但在对3%酒精有成熟偏好的大鼠中则无活性。这些数据可能表明7-羟基二苯丙氨酸在酒精滥用和依赖情况下的应用有限。
