Arpa J, Palomo F, Gutiérrez Molina M, Morales C, Alonso de Leciñana M, Barreiro P
Servicio de Neurología, Hospital La Paz, Universidad Autónoma de Madrid.
Neurologia. 1994 Nov;9(9):423-6.
We diagnosed idiopathic granulomatous angiitis of the central nervous system in a 51-year-old man by leptomeningeal and cortical biopsy. The patient's disease was prolonged, with symptoms recurring over a period of 15 years. Treatment with prednisone and cyclophosphamide produced total remission after a follow-up of 22 months. Computerized tomography was less sensitive and revealed fewer lesions than did magnetic resonance imaging. Angiography was not sensitive and leptomeningeal and cortical biopsy were essential for diagnosis in this patient.
我们通过软脑膜和皮质活检，诊断出一名51岁男性患有特发性中枢神经系统肉芽肿性血管炎。该患者病程迁延，症状反复出现长达15年。泼尼松和环磷酰胺治疗后，经过22个月的随访实现了完全缓解。计算机断层扫描的敏感性较低，与磁共振成像相比显示出的病变较少。血管造影不敏感，软脑膜和皮质活检对该患者的诊断至关重要。
