McIntyre P B, Pemberton J H, Wolff B G, Dozois R R, Beart R W
Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota 55905.
Dis Colon Rectum. 1995 Jan;38(1):51-4. doi: 10.1007/BF02053857.
Uncertainty persists concerning the long-term results of ileal pouch-anal anastomosis performed for indeterminate colitis.
This study was designed to compare functional outcomes of ileal pouch-anal anastomosis in patients with typical chronic ulcerative colitis and indeterminate colitis.
Seventy-one ileoanal pouch patients were identified with a diagnosis of indeterminate colitis. Mean follow-up was 56 months. Outcomes were compared with 1,232 chronic ulcerative colitis patients after ileal pouch-anal anastomosis. Mean follow-up was 60 months.
(mean +/- SD) There was no difference in the frequency of daily bowel movements (indeterminate colitis, 7 +/- 3, vs. chronic ulcerative colitis, 7 +/- 2). Daytime and nighttime incontinence rates were likewise similar. Prevalence of pouchitis was identical (33 percent). However, failure rate was higher in the indeterminate colitis group (indeterminate colitis, 19 percent, vs. chronic ulcerative colitis, 8 percent; (P = 0.03)).
At a mean of nearly five years after surgery, failure appears to occur more frequently in patients with indeterminate colitis than in patients with chronic ulcerative colitis. However, the great majority of indeterminate colitis patients (> 80 percent) have long-term functional results identical to those of patients with chronic ulcerative colitis.
关于为不确定性结肠炎施行回肠贮袋肛管吻合术的长期结果仍存在不确定性。
本研究旨在比较典型慢性溃疡性结肠炎患者和不确定性结肠炎患者行回肠贮袋肛管吻合术的功能结局。
确定71例诊断为不确定性结肠炎的回肠贮袋患者。平均随访56个月。将结局与1232例行回肠贮袋肛管吻合术的慢性溃疡性结肠炎患者进行比较。平均随访60个月。
（均值±标准差）每日排便次数无差异（不确定性结肠炎，7±3次，对比慢性溃疡性结肠炎，7±2次）。白天和夜间失禁率同样相似。袋炎患病率相同（33%）。然而，不确定性结肠炎组的失败率更高（不确定性结肠炎，19%，对比慢性溃疡性结肠炎，8%；（P = 0.03））。
在术后平均近五年时，不确定性结肠炎患者的失败似乎比慢性溃疡性结肠炎患者更频繁发生。然而，绝大多数不确定性结肠炎患者（>80%）的长期功能结果与慢性溃疡性结肠炎患者相同。
