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卡托普利和吲哚美辛成功治疗芬兰先天性肾病综合征

Successful treatment of Finnish congenital nephrotic syndrome with captopril and indomethacin.

作者信息

Pomeranz A, Wolach B, Bernheim J, Korzets Z, Bernheim J

机构信息

Department of Nephrology, Meir General Hospital, Kfar Saba, Israel.

出版信息

J Pediatr. 1995 Jan;126(1):140-2. doi: 10.1016/s0022-3476(95)70518-x.

DOI:10.1016/s0022-3476(95)70518-x
PMID:7815205
Abstract

Two infants with biopsy-proven microcystic Finnish congenital nephrotic syndrome (onset at birth) were treated with a combination of captopril and indomethacin for 2 1/2 and 2 years, respectively; they had a marked reduction of urinary protein excretion without further need for albumin infusions. One infant has end-stage renal disease; the other infant's glomerular filtration rate has remained within normal limits.

摘要

两名经活检证实为微囊性芬兰先天性肾病综合征(出生时起病)的婴儿,分别接受了卡托普利和吲哚美辛联合治疗2.5年和2年;他们的尿蛋白排泄显著减少,无需再输注白蛋白。一名婴儿患有终末期肾病;另一名婴儿的肾小球滤过率仍在正常范围内。

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