Imada S, Yokota T, Hidaka T, Tamura K
Department of Internal Medicine, Miyazaki Prefectural Hospital, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Nov;32(11):1099-103.
A 81-year-old man was admitted to the hospital because he complained of hoarseness. Chest radiography showed a mass in the right upper mediastinum. An operation was done to remove the mass and make a conclusive diagnosis. Histologically, the tumor tissue consisted of spindle-shaped fibroblast-like cells and round histiocyte-like cells with bizarre giant cells. Part of the tissue had a storiform pattern. These findings led a diagnosis of malignant fibrous histiocytoma (MFH) of the "usual type". MFH is known to occur frequently in the soft tissues of extremities, trunk, and retroperitoneum, but it is seldom detected in the mediastinum. We report here a rare case of primary MFH in the mediastinum.
一名81岁男性因声音嘶哑入院。胸部X线检查显示右上纵隔有一肿块。进行了手术以切除肿块并做出明确诊断。组织学上，肿瘤组织由梭形的成纤维细胞样细胞和圆形的组织细胞样细胞以及奇异的巨细胞组成。部分组织呈席纹状排列。这些发现导致诊断为“普通型”恶性纤维组织细胞瘤（MFH）。已知MFH在四肢、躯干和腹膜后的软组织中频繁发生，但在纵隔中很少被检测到。我们在此报告一例罕见的纵隔原发性MFH病例。
