Julian M, Pieraggi M T, Bouissou H
Pathol Biol (Paris). 1976 May;24(5):355-8.
Deep, constant, extensive atherosclerosis can be experimentally induced on rats that are atheroresistant. Two main factors are involved in this experimentation; parietal alteration following chronic intoxication with BAPN (9 weeks) and a metabolic factor with hyperlipidic diet, but this metabolic damage should be sustained for a long time (40 weeks).
在具有抗动脉粥样硬化能力的大鼠身上,可以通过实验诱导出深度、持续性、广泛性的动脉粥样硬化。该实验涉及两个主要因素:用β-氨基丙腈(BAPN)进行慢性中毒(9周)后的血管壁改变,以及高脂饮食引发的代谢因素,但这种代谢损伤应持续较长时间(40周)。