Assion H J, Heinemann F
Psychiatrische Universitätsklinik, Bonn.
Nervenarzt. 1994 Nov;65(11):795-7.
This paper reports on a case of spasmodic torticollis after longterm treatment with neuroleptics. This form of dystonia is called tardive dystonia to distinguish it from tardive dyskinesia. Its pathophysiology is unknown. Pathological changes are described in the basal ganglia. Increased signal was found on magnetic resonance imaging on both sides of the basal ganglia reflecting structural lesions. These structural changes, together with neuroleptic medication, represent predisposing factors for the manifestation of tardive dystonia.
本文报告了一例长期使用抗精神病药物治疗后出现痉挛性斜颈的病例。这种肌张力障碍形式被称为迟发性肌张力障碍，以区别于迟发性运动障碍。其病理生理学尚不清楚。基底神经节有病理变化描述。磁共振成像显示基底神经节两侧信号增强，提示存在结构性病变。这些结构变化与抗精神病药物治疗一起，是迟发性肌张力障碍表现的诱发因素。
