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[绵羊狂蝇(羊狂蝇)幼虫寄生时的T细胞反应]

[The T-cell response in parasitization by sheep bot (Oestrus ovis) larvae].

作者信息

Marchenko V A, Marchenko V P

出版信息

Parazitologiia. 1994 Mar-Apr;28(2):156-66.

PMID:7816503
Abstract

The kinetics of immunocompetent cells in sheep artificially infested with 80, 160, 1000 specimens of Oestrus ovis larvae and immunized with antigen from larvae protein was traced by stableons (E-REC) and antigen-fixing (Ag-REC) rosette formation reaction. It was found that E-REC level changes only a little in both infested and reinfested animals. Ag-REC kinetics mates with the rated larvae biomass changes in all age groups. Ag-REC level of infested animals is much higher and then regularly declines in the following cycles of invasion. T-lymphocytes level and death level of immunized lambs is much higher than in intact animals at the beginning of parasitism.

摘要

通过稳定素(E-REC)和抗原固定(Ag-REC)玫瑰花结形成反应,追踪人工感染80、160、1000只羊狂蝇幼虫并接种幼虫蛋白抗原的绵羊体内免疫活性细胞的动力学变化。结果发现,无论是感染还是再次感染的动物,E-REC水平变化都很小。Ag-REC动力学与所有年龄组中额定幼虫生物量的变化相匹配。感染动物的Ag-REC水平要高得多,然后在随后的侵袭周期中定期下降。在寄生虫感染开始时,免疫羔羊的T淋巴细胞水平和死亡率远高于未感染动物。

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