Kane E, Peterson R A
Poult Sci. 1976 Jul;55(4):1580-2. doi: 10.3382/ps.0551580.
Salmonella typhimurium lipopolysaccharide was injected into the third cerebral ventricle of the hen via a surgically implanted cannula. Hens injected with 20-80 mug. Salmonella typhimurium lipopolysaccharide had higher (P less than .01) rectal temperatures (42.3 degrees C. compared to 41.3 degrees C.) than uninjected hens. Those injected with 0.9% NaCl had significantly lower (P less than .01) rectal temperatures (41.8 degrees C. compared to 42.3 degrees C.) than hens injected with this bacterial pyrogen. There is an indicated function for bacterial pyrogen acting directly in the hypothalamic area of the chicken.
通过手术植入的套管将鼠伤寒沙门氏菌脂多糖注入母鸡的第三脑室。注射20 - 80微克鼠伤寒沙门氏菌脂多糖的母鸡直肠温度（42.3摄氏度，相比之下未注射的母鸡为41.3摄氏度）高于未注射的母鸡（P < 0.01）。注射0.9%氯化钠的母鸡直肠温度（41.8摄氏度，相比之下注射这种细菌热原的母鸡为42.3摄氏度）显著低于注射这种细菌热原的母鸡（P < 0.01）。表明细菌热原在鸡的下丘脑区域直接发挥作用。
