Pienta K J, Demers R, Hoff M, Kau T Y, Montie J E, Severson R K
Genitourinary Oncology Program, MCF-Prentis Comprehensive Cancer Center of Metropolitan Detroit, Wayne State University, Detroit, Michigan.
Urology. 1995 Jan;45(1):93-101; discussion 101-2. doi: 10.1016/s0090-4295(95)96996-9.
Reports have demonstrated that African Americans diagnosed with prostate cancer have a poor survival compared with whites. We examined the impact of age, race, and stage of disease on survival for men diagnosed with prostate cancer.
A retrospective analysis was made of men diagnosed with prostate cancer utilizing the Surveillance, Epidemiology, and End Results Program (SEER) database. A total of 12,907 men (9339 white, 3568 black) diagnosed from January 1, 1973 through December 31, 1987 were included in the study. For each stage of disease, survival experience was examined using Kaplan-Meier and life table methods, followed by analysis using Cox's proportional hazard model.
African-American men have a poorer survival than whites for all stages of prostate cancer when the cancer is diagnosed at younger ages. These differences in survival were not demonstrated for men diagnosed with prostate cancer after age 70.
Age and race should be taken into account when assessing the survival of patients with prostate cancer.
报告显示，被诊断患有前列腺癌的非裔美国人与白人相比，生存率较低。我们研究了年龄、种族和疾病分期对被诊断患有前列腺癌男性生存率的影响。
利用监测、流行病学和最终结果计划（SEER）数据库对被诊断患有前列腺癌的男性进行回顾性分析。共有12907名男性（9339名白人，3568名黑人）纳入研究，这些男性于1973年1月1日至1987年12月31日期间被诊断。对于每个疾病分期，使用Kaplan-Meier法和生命表法检查生存情况，随后使用Cox比例风险模型进行分析。
当在较年轻时被诊断出前列腺癌时，非裔美国男性在前列腺癌各阶段的生存率均低于白人。70岁以后被诊断患有前列腺癌的男性未显示出生存率的这些差异。
在评估前列腺癌患者的生存率时，应考虑年龄和种族因素。
