Pate J W, Fabian T C, Walker W A
Cardiothoracic Surgery Section, College of Medicine, University of Tennessee, Memphis 38163.
Ann Thorac Surg. 1995 Jan;59(1):90-8; discussion 98-9. doi: 10.1016/0003-4975(94)00719-N.
In an attempt to prevent paraplegia, a devastating complication common after the repair of traumatic rupture of the aorta, we have used partial cardiopulmonary bypass. Most of the patients in our series (79.5%) underwent other major surgical procedures immediately before or after the aortic repair. Eight of the 110 patients died before aortic repair could be performed. The aorta was not repaired in 3, because of other injuries. In 9, the repair was done without a shunt or bypass; 4 patients died and 2 (22.2%) survived without paraplegia. One of the 2 who underwent repair with a Gott shunt died; the survivor suffered no cord damage. Of the 88 patients whose repair was carried out under cardiopulmonary bypass, 6 died and 80 (90.9%) survived without paraplegia. None of the last 39 patients has become paraplegic, as vasodilator treatment is now discontinued during the cross-clamp period. Serious intracranial injury was present in 19 patients; in 3 (15.8%) the injury became worse after repair. There was no evidence of new or increased intraabdominal bleeding during heparinization. Except in the event of pulmonary lacerations, systemic heparin therapy was not associated with major problems.
为预防截瘫这一主动脉创伤性破裂修复术后常见的灾难性并发症,我们采用了部分体外循环。我们系列研究中的大多数患者(79.5%)在主动脉修复术前或术后立即接受了其他重大外科手术。110例患者中有8例在进行主动脉修复前死亡。3例因其他损伤未进行主动脉修复。9例在无分流或体外循环的情况下进行了修复;4例死亡,2例(22.2%)存活且无截瘫。2例采用戈特分流术进行修复的患者中有1例死亡;幸存者未发生脊髓损伤。在88例接受体外循环下修复的患者中,6例死亡,80例(90.9%)存活且无截瘫。由于目前在阻断主动脉期间停用了血管扩张剂治疗,最后39例患者均未发生截瘫。19例患者存在严重颅脑损伤;3例(15.8%)在修复后损伤加重。肝素化期间未发现新的或增加的腹腔内出血迹象。除肺裂伤外,全身肝素治疗未引发重大问题。