Siegel M E, Wagner H N
Semin Nucl Med. 1976 Jul;6(3):253-78. doi: 10.1016/s0001-2998(76)80008-6.
The use of radioactive tracers in the diagnostic and therapeutic evaluation of the patient with peripheral arterial or venous disease has proven to be clinically useful. Their application has provided a means by which the regional distribution of perfusion at the level of the microcirculation, at rest and under various stresses, can be assessed. Graft patency can be determined simply and repeatedly, and the relative perfusion of "ischemic" ulcers can be used to assess their healing potential. The presence of arteriovenous shunts can be verified, localized, and quantified. Venous thrombi can be detected, and the competence of the venous valvular system and muscle pump as well as the hemodynamics of the venous system can be quantified.
放射性示踪剂在周围动脉或静脉疾病患者的诊断和治疗评估中的应用已被证明具有临床实用性。它们的应用提供了一种手段,通过该手段可以评估微循环水平在静息状态和各种应激条件下的灌注区域分布。可以简单且反复地确定移植血管的通畅情况,并且“缺血性”溃疡的相对灌注可用于评估其愈合潜力。动静脉分流的存在可以得到证实、定位和量化。可以检测静脉血栓,并且可以量化静脉瓣膜系统和肌肉泵的功能以及静脉系统的血流动力学。