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丙酸倍他米松软膏治疗银屑病和特应性皮炎:一项双盲研究。

Betamethasone dipropionate ointment in the treatment of psoriasis and atopic dermatitis: a double-blind study.

作者信息

Vanderploeg D E

出版信息

South Med J. 1976 Jul;69(7):862-3. doi: 10.1097/00007611-197607000-00017.

Abstract

This report describes the use of a new corticosteroid ointment in the treatment of psoriasis and atopic dermatitis. It further summarizes the results of treatment with the active medication versus the vehicle alone in these two disease categories. In the group with psoriasis 13 of 17 patients (76.4%) treated with the active drug showed either excellent or good clinical response (50% to 100% improvement) in three weeks. Five of 16 patients (31.2%) treated with the placebo showed excellent or good response. In the group with atopic dermatitis 16 of 17 patients (94.1%) treated with the active drug showed either excellent or good clinical response (50% to 100% improvement) in three weeks. Two of 16 (12.5%) treated with the placebo showed excellent or good response.

摘要

本报告描述了一种新型皮质类固醇软膏在治疗银屑病和特应性皮炎中的应用。它进一步总结了在这两种疾病类别中使用活性药物与单独使用赋形剂治疗的结果。在银屑病组中,17例接受活性药物治疗的患者中有13例(76.4%)在三周内表现出优异或良好的临床反应(改善50%至100%)。16例接受安慰剂治疗的患者中有5例(31.2%)表现出优异或良好的反应。在特应性皮炎组中,17例接受活性药物治疗的患者中有16例(94.1%)在三周内表现出优异或良好的临床反应(改善50%至100%)。16例接受安慰剂治疗的患者中有2例(12.5%)表现出优异或良好的反应。

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