Feldmeier H, Krantz I, Poggensee G
Fachbereich Grundlagenmedizin, Freie Universität Berlin, Germany.
Int J STD AIDS. 1994 Sep-Oct;5(5):368-72. doi: 10.1177/095646249400500517.
Sexually transmitted diseases increase the probability for HIV transmission, presumably through lesions in the genital mucosa. Female genital schistosomiasis, a special form of urinary schistosomiasis due to infection with Schistosoma haematobium, may be another risk-factor for transmission of HIV. From published data there seem to be pathophysiological, immunological and epidemiological evidence for an association between genital ulcer disease due to S. haematobium and HIV-infection in women. Female genital schistosomiasis could be seen as an example of how an interaction between a parasitic disease and HIV facilitates the propagation of the latter. As long as the prevalence of HIV is low in the general population, interventions targeted to high risk groups will significantly delay, or even prevent, widespread dissemination of the HIV infection in the rest of the population. If female genital schistosomiasis is a risk factor for the spread of HIV like other genital ulcer diseases, there should be interesting ways to intervene from the public health point of view.
性传播疾病会增加艾滋病毒传播的可能性，大概是通过生殖器黏膜的损伤。女性生殖器血吸虫病是由于感染埃及血吸虫而导致的一种特殊形式的泌尿系统血吸虫病，可能是艾滋病毒传播的另一个危险因素。从已发表的数据来看，似乎有病理生理学、免疫学和流行病学证据表明，由埃及血吸虫引起的生殖器溃疡病与女性艾滋病毒感染之间存在关联。女性生殖器血吸虫病可被视为一种寄生虫病与艾滋病毒之间的相互作用如何促进后者传播的例子。只要艾滋病毒在普通人群中的流行率较低，针对高危人群的干预措施将显著延迟甚至预防艾滋病毒在其他人群中的广泛传播。如果女性生殖器血吸虫病像其他生殖器溃疡病一样是艾滋病毒传播的危险因素，那么从公共卫生的角度来看，应该有一些有趣的干预方法。
