Receveur M C, Quiniou J M, Delprat P, Monlun E, Lehner V, Le Bras M
Smith Kline Laboratoires pharmaceutiques, Nanterre.
Bull Soc Pathol Exot. 1993;86(5 Pt 2):406-9.
Simultaneous vaccination against hepatitis A and yellow fever has been studied in our unit: Santé-Voyage, Bordeaux. This randomised study included 108 healthy subjects: 36 received hepatitis A vaccine (Havrix, SKF), 36 received yellow fever vaccine and 36 received both. For hepatitis A vaccine protocol comprised one injection at day zero, one at D15, and one booster dose at 6 months. Those who received yellow fever vaccine had it at D0. Simultaneous vaccination is well tolerated and immunogenicity is as good as it is for each vaccine separately. This is particularly interesting for tropical travellers who are at risk for hepatitis A.
我们位于波尔多的“健康之旅”（Santé-Voyage）机构对甲型肝炎和黄热病联合疫苗接种进行了研究。这项随机研究纳入了108名健康受试者：36人接种甲型肝炎疫苗（Havrix，SKF公司生产），36人接种黄热病疫苗，36人同时接种两种疫苗。甲型肝炎疫苗接种方案为在第0天注射一剂，第15天注射一剂，6个月时注射一剂加强针。接种黄热病疫苗的人在第0天接种。联合疫苗接种耐受性良好，免疫原性与分别接种每种疫苗时相当。这对于有甲型肝炎感染风险的热带旅行者来说尤其有意义。
