Poser C M, Vernant J C
Department of Neurology, Harvard Medical School, Boston, MA.
Bull Soc Pathol Exot. 1993;86(5 Pt 2):428-32.
Numerous epidemiological studies showed that The occurrence of multiple sclerosis (MS) was the result of genetic factors varying by ethnic group as well as geographical and environmental factors. It is difficult to estimate exactly the prevalence of MS among black Africans. Nevertheless it's possible to state that the disease is rare but present among those populations. Among black Americans prevalence of MS seems related to the degree of mixture with white population. Among West Indians the occurrence of MS is closely related to an environmental factor acquired in Europe before 15 years of age. Those data confirm the existence during childhood and adolescence of a critical period during which an environmental factor is acquired in regions of high prevalence for MS.
众多流行病学研究表明,多发性硬化症(MS)的发生是遗传因素(因种族而异)以及地理和环境因素共同作用的结果。很难准确估计非洲黑人中MS的患病率。然而,可以确定的是,这种疾病在这些人群中很罕见但确实存在。在美国黑人中,MS的患病率似乎与和白人的混血程度有关。在西印度群岛人中,MS的发生与15岁之前在欧洲获得的一种环境因素密切相关。这些数据证实了在儿童期和青少年期存在一个关键时期,在此期间在MS高流行地区会获得一种环境因素。