Pinkerton P H
Department of Laboratory Haematology, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.
Transfus Med. 1994 Sep;4(3):231-6. doi: 10.1111/j.1365-3148.1994.tb00277.x.
Two years' experience with a hospital-based autologous blood donor programme is described. Of 511 patients enrolled, 86% underwent surgery without use of allogeneic blood, and 19% of collected units were not used. For six common procedures, a 'target' autologous blood schedule of 2 or 3 units (depending on the procedure) was set. If an extra unit for each of 407 patients had been collected (i.e. 3 or 4), an additional 20 patients would have been protected from exposure to allogeneic blood at a cost of 387 unnecessary collections. The difference between the mean haemoglobin (Hb) concentration at entry to the programme and the mean pre-operative Hb concentration was not clinically important and only 25 of 511 patients were deferred on account of anaemia after one or more donations. The autologous blood used represents 3.8% of the units of blood or packed red blood cells transfused during the 2 years of study. Adverse (vasovagal) reactions were infrequent (2.2%) in spite of liberal acceptance criteria.
本文描述了一项基于医院的自体输血计划的两年经验。在纳入的511例患者中，86%的患者在手术中未使用异体血，所采集的单位中有19%未被使用。对于六种常见手术，设定了一个“目标”自体输血计划，即根据手术不同采集2或3个单位（取决于手术类型）。如果为407例患者中的每一位多采集一个单位（即3或4个单位），则可以额外保护20例患者避免接触异体血，代价是387次不必要的采集。进入该计划时的平均血红蛋白（Hb）浓度与术前平均Hb浓度之间的差异在临床上并不重要，511例患者中只有25例在一次或多次献血后因贫血而延期。在两年的研究期间，所使用的自体血占输注的全血或红细胞单位的3.8%。尽管接受标准宽松，但不良（血管迷走性）反应并不常见（2.2%）。
