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择期子宫切除术前的术前自体血捐献。

Preoperative autologous blood donations before elective hysterectomy.

作者信息

Kanter M H, van Maanen D, Anders K H, Castro F, Mya W W, Clark K

机构信息

Kaiser Permanente Medical Center, Woodland Hills, CA, USA.

出版信息

JAMA. 1996 Sep 11;276(10):798-801.

PMID:8769589
Abstract

OBJECTIVE

To determine whether preoperative autologous blood donation is justified for patients undergoing elective abdominal or vaginal hysterectomy.

DESIGN

Retrospective cohort study.

PATIENTS AND SETTING

A total of 263 consecutive patients admitted for elective abdominal or vaginal hysterectomy to a community health maintenance organization hospital during 1993 and 1994.

MAIN OUTCOME MEASURES

Evaluation of transfusion rates for patients who did and did not donate autologous blood; determination of any risk factors that would predict the need for transfusion; and evaluation of the need for transfusion based on chart review.

RESULTS

Of 263 patients, 26 received a blood transfusion. The major risk factor identified for transfusion was the donation of autologous blood. Of 140 patients who donated autologous blood, 25 were transfused, whereas just 1 patient of 123 who did not donate autologous blood was transfused (P<.001). Patients who donated autologous blood had significantly lower mean admission hemoglobin level than patients who did not donate (119 g/L vs 132 g/L; P<.05); logistic regression showed that autologous donation was an independent risk factor for transfusion.

CONCLUSION

For hysterectomy patients, donation of autologous blood causes anemia and is associated with a more liberal transfusion policy. These 2 factors result in a markedly increased incidence of transfusion with its associated risks. Elimination of preoperative autologous donation for these patients should not result in frequent exposure to allogeneic blood.

摘要

目的

确定择期行腹部或阴道子宫切除术的患者术前自体血捐献是否合理。

设计

回顾性队列研究。

患者与研究地点

1993年至1994年期间,一家社区健康维护组织医院连续收治的263例择期行腹部或阴道子宫切除术的患者。

主要观察指标

评估自体血捐献和未捐献患者的输血率;确定任何可预测输血需求的危险因素;通过病历审查评估输血需求。

结果

263例患者中,26例接受了输血。确定的输血主要危险因素是自体血捐献。140例自体血捐献患者中,25例接受了输血,而1并不接受输血,患者接受输血(P<0.001)。自体血捐献患者的平均入院血红蛋白水平显著低于未捐献患者(119 g/L对132 g/L;P<0.05);逻辑回归显示自体血捐献是输血的独立危险因素。

结论

对于子宫切除术患者,自体血捐献会导致贫血,并与更宽松的输血政策相关。这两个因素导致输血发生率及其相关风险显著增加。取消这些患者的术前自体血捐献不应导致频繁接触异体血。 23例未捐献自体血的患者中只有1例接受了输血(P<0.001)。自体血捐献患者的平均入院血红蛋白水平显著低于未捐献患者(119 g/L对132 g/L;P<0.05);逻辑回归显示自体血捐献是输血的独立危险因素。

结论

对于子宫切除术患者,自体血捐献会导致贫血,并与更宽松的输血政策相关。这两个因素导致输血发生率及其相关风险显著增加。取消这些患者的术前自体血捐献不应导致频繁接触异体血。

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