Kanter M H, van Maanen D, Anders K H, Castro F, Mya W W, Clark K
Kaiser Permanente Medical Center, Woodland Hills, CA, USA.
JAMA. 1996 Sep 11;276(10):798-801.
To determine whether preoperative autologous blood donation is justified for patients undergoing elective abdominal or vaginal hysterectomy.
Retrospective cohort study.
A total of 263 consecutive patients admitted for elective abdominal or vaginal hysterectomy to a community health maintenance organization hospital during 1993 and 1994.
Evaluation of transfusion rates for patients who did and did not donate autologous blood; determination of any risk factors that would predict the need for transfusion; and evaluation of the need for transfusion based on chart review.
Of 263 patients, 26 received a blood transfusion. The major risk factor identified for transfusion was the donation of autologous blood. Of 140 patients who donated autologous blood, 25 were transfused, whereas just 1 patient of 123 who did not donate autologous blood was transfused (P<.001). Patients who donated autologous blood had significantly lower mean admission hemoglobin level than patients who did not donate (119 g/L vs 132 g/L; P<.05); logistic regression showed that autologous donation was an independent risk factor for transfusion.
For hysterectomy patients, donation of autologous blood causes anemia and is associated with a more liberal transfusion policy. These 2 factors result in a markedly increased incidence of transfusion with its associated risks. Elimination of preoperative autologous donation for these patients should not result in frequent exposure to allogeneic blood.
确定择期行腹部或阴道子宫切除术的患者术前自体血捐献是否合理。
回顾性队列研究。
1993年至1994年期间,一家社区健康维护组织医院连续收治的263例择期行腹部或阴道子宫切除术的患者。
评估自体血捐献和未捐献患者的输血率;确定任何可预测输血需求的危险因素;通过病历审查评估输血需求。
263例患者中,26例接受了输血。确定的输血主要危险因素是自体血捐献。140例自体血捐献患者中,25例接受了输血,而1并不接受输血,患者接受输血(P<0.001)。自体血捐献患者的平均入院血红蛋白水平显著低于未捐献患者(119 g/L对132 g/L;P<0.05);逻辑回归显示自体血捐献是输血的独立危险因素。
对于子宫切除术患者,自体血捐献会导致贫血,并与更宽松的输血政策相关。这两个因素导致输血发生率及其相关风险显著增加。取消这些患者的术前自体血捐献不应导致频繁接触异体血。 23例未捐献自体血的患者中只有1例接受了输血(P<0.001)。自体血捐献患者的平均入院血红蛋白水平显著低于未捐献患者(119 g/L对132 g/L;P<0.05);逻辑回归显示自体血捐献是输血的独立危险因素。
对于子宫切除术患者,自体血捐献会导致贫血,并与更宽松的输血政策相关。这两个因素导致输血发生率及其相关风险显著增加。取消这些患者的术前自体血捐献不应导致频繁接触异体血。