de Silva H J, Senanayake N
Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Ceylon Med J. 1994 Sep;39(3):135-7.
We describe 14 Sinhalese male patients with hypokalaemic periodic paralysis (HPP). The age at onset was between 10 and 32 years. Each paralytic episode lasted from 6 to 48 hours (except in one patient who had an attack lasting 5 days). The frequency of attacks varied from 8 to 10 per month in one patient to only 2 attacks over a period of 16 years in another. Four patients (28.6%) had a family history of the disease. Hypokalaemia (serum potassium 1.5 to 3 mmol/l) was documented during an attack in 11 patients. No cause for hypokalaemia was evident in any of them. Investigations including EMG, thyroid hormone level and skeletal muscle histology were within normal limits between episodes. All the patients responded well to treatment with potassium supplementation, alone or with acetazolamide.
我们描述了14例患有低钾性周期性麻痹（HPP）的僧伽罗男性患者。发病年龄在10至32岁之间。每次麻痹发作持续6至48小时（有1例患者发作持续5天除外）。发作频率从1例患者每月8至10次到另一例患者在16年期间仅发作2次不等。4例患者（28.6%）有该病的家族史。11例患者在发作期间记录到低钾血症（血清钾1.5至3 mmol/L）。他们中没有一人有明显的低钾血症病因。发作间期包括肌电图、甲状腺激素水平和骨骼肌组织学在内的检查均在正常范围内。所有患者单独补充钾或联合乙酰唑胺治疗反应良好。
