Nozaki S, Kang J, Miyai I, Matsumura T
Department of Neurology, Toneyama National Hospital.
Rinsho Shinkeigaku. 1994 Sep;34(9):922-4.
The feasibility of using electroglottography (EGG) to record and measure aspects of swallowing was tested in 31 patients with Parkinson's disease (72.8 +/- 4.8 years) and 10 control subjects (74.6 +/- 4.4 years). The patients were divided into three groups: those feeling dysphagia frequently (D(+), n = 9), those feeling dysphagia occasionally (D(+/-), n = 8), and those not feeling dysphagia (D(-), n = 14). The instrument delivered a 250 microA, 52 kHz carrier signal to a pair of surface electrodes on each side of the larynx at the level of the thyroid lamina. Tissue impedance across the neck was recorded via EGG while the swallowing of 10 ml of water. Four trials were performed for each subject. Based on the analysis of EGG waveform, latency, number of phases and duration were measured. In the EEGs of D(+) group, the reproducibility of waveforms was poor, while the waveforms of D(-) group and control group showed higher reproducibility. The waveforms of D(+) group had significantly longer latency and more phases than those of D(-) and control groups. In D(+), the duration was significantly longer than that of control group. These results suggest that the EGG is a quantitative and noninvasive technique for analysis of swallowing in patients with Parkinson's disease.
在31例帕金森病患者（72.8±4.8岁）和10名对照受试者（74.6±4.4岁）中测试了使用电子喉图（EGG）记录和测量吞咽相关方面的可行性。患者被分为三组：经常感到吞咽困难的患者（D(+)，n = 9）、偶尔感到吞咽困难的患者（D(+/-)，n = 8）以及未感到吞咽困难的患者（D(-)，n = 14）。该仪器将250微安、52千赫兹的载波信号输送到甲状腺板水平喉部两侧的一对表面电极上。在吞咽10毫升水时，通过EGG记录颈部的组织阻抗。对每个受试者进行了四次试验。基于EGG波形分析，测量了潜伏期、相数和持续时间。在D(+)组的电子喉图中，波形的可重复性较差，而D(-)组和对照组的波形显示出较高的可重复性。D(+)组的波形潜伏期明显长于D(-)组和对照组，相数也更多。在D(+)组中，持续时间明显长于对照组。这些结果表明，EGG是一种用于分析帕金森病患者吞咽情况的定量且非侵入性技术。
