Frolov V A, Ramdavon P, Bakhilov V L
Patol Fiziol Eksp Ter. 1994 Jul-Sep(3):23-6.
The contractile and ultrastructural parameters of the left and right ventricles were studied in rabbits 3 weeks after ascending aortic coarctation by a third of the baseline diameter. In other rabbits, the same parameters were studied 1, 2, 3, and 4 weeks after recovery of the normal aortic lumen following three weeks of its narrowing. It was found that a rapid recovery of the parameters under study did not occur after decoarctation despite the fact that left ventricular overload was abolished. A fortnight after decoarctation there was a profound increase in the contractility of the two ventricles and three weeks there was a significant enhancement of cardiomyocytic mitochondrial function.
在升主动脉缩窄至基线直径的三分之一后3周,研究了兔左、右心室的收缩和超微结构参数。在其他兔子中,在主动脉管腔狭窄三周后恢复正常主动脉管腔的1、2、3和4周,研究了相同的参数。结果发现,尽管左心室负荷已消除,但解除缩窄后所研究的参数并未迅速恢复。解除缩窄两周后,两个心室的收缩力显著增加,三周后心肌细胞线粒体功能显著增强。