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[升主动脉缩窄与解除缩窄时左右心室功能和形态学参数的相互关系动态变化]

[Dynamics of the interrelationships of functional and morphologic parameters of the left and right ventricle in coarctation and decoarctation of the ascending aorta].

作者信息

Frolov V A, Ramdavon P, Bakhilov V L

出版信息

Patol Fiziol Eksp Ter. 1994 Jul-Sep(3):23-6.

PMID:7824337
Abstract

The contractile and ultrastructural parameters of the left and right ventricles were studied in rabbits 3 weeks after ascending aortic coarctation by a third of the baseline diameter. In other rabbits, the same parameters were studied 1, 2, 3, and 4 weeks after recovery of the normal aortic lumen following three weeks of its narrowing. It was found that a rapid recovery of the parameters under study did not occur after decoarctation despite the fact that left ventricular overload was abolished. A fortnight after decoarctation there was a profound increase in the contractility of the two ventricles and three weeks there was a significant enhancement of cardiomyocytic mitochondrial function.

摘要

在升主动脉缩窄至基线直径的三分之一后3周,研究了兔左、右心室的收缩和超微结构参数。在其他兔子中,在主动脉管腔狭窄三周后恢复正常主动脉管腔的1、2、3和4周,研究了相同的参数。结果发现,尽管左心室负荷已消除,但解除缩窄后所研究的参数并未迅速恢复。解除缩窄两周后,两个心室的收缩力显著增加,三周后心肌细胞线粒体功能显著增强。

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