孤立性肺结节：动态增量CT评估的初步研究
Solitary pulmonary nodule: preliminary study of evaluation with incremental dynamic CT.
作者信息
Yamashita K, Matsunobe S, Tsuda T, Nemoto T, Matsumoto K, Miki H, Konishi J
机构信息
Department of Radiology, Shiga Health Insurance Hospital, Otsu, Japan.
出版信息
Radiology. 1995 Feb;194(2):399-405. doi: 10.1148/radiology.194.2.7824717.
PURPOSE
To use incremental dynamic computed tomography (CT) to evaluate solitary pulmonary nodules (SPNs).
MATERIALS AND METHODS
Thirty-two adult patients with SPNs less than 3 cm in diameter had 18 primary lung cancers, 10 tuberculomas, and four hamartomas. The CT numbers of the inner area of the nodule were calculated before and 30 seconds, 2 minutes, and 5 minutes after administration of contrast material.
RESULTS
All lung cancers and one of four hamartomas showed significantly greater enhancement (P < .0001) than benign SPNs, which did not show enhancement (except for one hamartoma). All lung cancers and one of four hamartomas showed complete enhancement, one hamartoma showed peripheral enhancement, two hamartomas and eight of 10 tuberculomas showed capsular enhancement, and two tuberculomas showed no enhancement.
CONCLUSION
Maximum attenuation of 20-60 HU appears to be a good predictor of malignancy.
目的
采用动态增强计算机断层扫描（CT）评估孤立性肺结节（SPN）。
材料与方法
32例直径小于3 cm的成人SPN患者，其中原发性肺癌18例，结核瘤10例，错构瘤4例。在注射造影剂前及注射后30秒、2分钟和5分钟计算结节内部区域的CT值。
结果
所有肺癌及4例错构瘤中的1例表现出明显高于良性SPN的强化（P < .0001），良性SPN未表现出强化（1例错构瘤除外）。所有肺癌及4例错构瘤中的1例表现为完全强化，1例错构瘤表现为周边强化，2例错构瘤及10例结核瘤中的8例表现为包膜强化，2例结核瘤无强化。
结论
最大强化值20 - 60 HU似乎是恶性肿瘤的良好预测指标。
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