Mikheev N B
At Energy Rev. 1976 Mar;14(1):3-36.
Radioactive colloidal solutions and suspensions are being widely used in the diagnosis and treatment of various diseases. The author considers the behaviour or radioactive disperse preparations in the body and devotes particular attention to the reasons for isotope transition from the colloidal to the ionic state. Questions concerned with producing and investigating radioactive colloidal solutions are discussed. In the light of the physical and chemical properties of the radioisotopes and of the disperse systems themselves, the author considers methods of producing the more important radioactive disperse preparations: colloidal solutions of noble metals; colloidal solutions containing phosphorus-32, yttrium-90 and isotopes of the rare-earth elements; colloidal solutions with with indium-113m, gallium-68, technetium-99m and rhenium-186; suspensions (macroaggregates and microspheres) for the diagnosis of lung diseases; and radioactive colloidal solutions based on quaternary ammonium base compounds.
放射性胶体溶液和悬浮液正广泛应用于各种疾病的诊断和治疗。作者研究了放射性分散制剂在体内的行为，并特别关注同位素从胶体状态转变为离子状态的原因。文中讨论了有关制备和研究放射性胶体溶液的问题。根据放射性同位素和分散体系本身的物理化学性质，作者考虑了制备更重要的放射性分散制剂的方法：贵金属胶体溶液；含磷-32、钇-90和稀土元素同位素的胶体溶液；含铟-113m、镓-68、锝-99m和铼-186的胶体溶液；用于诊断肺部疾病的悬浮液（大聚集体和微球）；以及基于季铵碱化合物的放射性胶体溶液。
