Ueno H, Ariji E, Tanaka T, Kanda S, Mori S, Goto M, Mizuno A, Okabe H, Nakamura T
Department of Radiology, Nagasaki University School of Dentistry, Japan.
Skeletal Radiol. 1994 Oct;23(7):509-12. doi: 10.1007/BF00223079.
We report two cases of osteoblastoma, one of them an unusual case in a 32-year-old woman in whom a maxillary tumor was confidently diagnosed as an osteoblastoma at the time of primary excision and subsequently transformed into an osteosarcoma 7 years after the onset of clinical symptoms. The other patient developed osteosarcoma arising in the maxilla, which was diagnosed 3 years after the primary excision and is very suggestive of malignant transformation in osteoblastoma. We present the radiological features, including computed tomographic and magnetic resonance imaging studies, of this unusual event of transformed tumor and compare imaging features of benign and dedifferentiated counterparts of this rare tumor complex.
我们报告了两例骨母细胞瘤病例,其中一例为32岁女性的罕见病例,其上颌肿瘤在初次切除时被确诊为骨母细胞瘤,临床症状出现7年后转变为骨肉瘤。另一例患者上颌骨发生骨肉瘤,在初次切除3年后被诊断出来,这强烈提示骨母细胞瘤发生了恶性转化。我们展示了这种肿瘤转变这一罕见事件的影像学特征,包括计算机断层扫描和磁共振成像研究,并比较了这种罕见肿瘤复合体的良性和去分化对应物的影像学特征。