Collins J G
Department of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut.
Yale J Biol Med. 1993 Sep-Oct;66(5):457-62.
The clinical success of perispinal administration of opiates for pain relief has demonstrated the power of manipulating the neurochemistry of the spinal cord. This article briefly discussed reasons for increased interest in new spinal agents and some of the issues associated with determining their clinical safety.
脊柱周围注射阿片类药物用于缓解疼痛的临床成功证明了调控脊髓神经化学的作用。本文简要讨论了对新型脊柱药物兴趣增加的原因以及与确定其临床安全性相关的一些问题。
