Agrez M V, Meldrum C J, Sim A T, Aebersold R H, Clark I M, Cawston T E, Burns G F
Faculty of Medicine, University of Newcastle, N.S.W., Australia.
Biochem Biophys Res Commun. 1995 Jan 17;206(2):590-600. doi: 10.1006/bbrc.1995.1084.
We have previously reported that human colon cancer cells secrete a factor(s) which induces elongation of colon fibroblasts in vitro. Isolation of this factor led to the identification of a 55kD protein with fibroblast stretching activity. Two internal amino acid sequences identified in this protein (YEI; GFQALGDAADI) share complete homology with tissue inhibitor of metalloproteinase (TIMP-1).
