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动脉重建手术对严重下肢缺血结局的影响。

The influence of arterial reconstructive surgery on the outcome of critical leg ischaemia.

作者信息

Luther M

机构信息

Surgical Department, Vasa Central Hospital, Finland.

出版信息

Eur J Vasc Surg. 1994 Nov;8(6):682-9. doi: 10.1016/s0950-821x(05)80647-4.

DOI:10.1016/s0950-821x(05)80647-4
PMID:7828744
Abstract

OBJECTIVES

To analyse the effect of an aggressive vascular reconstruction policy on the outcome of critical leg ischaemia in a defined population.

DESIGN

A retrospective survey of surgical in-hospital patient data related to population data in the study region over 22 years (1970-1991).

SETTING

Vasa Central Hospital district in Western Finland. The area is served by one Central Hospital and two District Hospitals.

MATERIALS

The population of 165,000 at the beginning of the study and 178,000 at the end of the study needing 977 interventions for chronic critical leg ischemia (CLI), 397 for acute ischaemia and 313 for noncritical leg ischemia.

CHIEF OUTCOME MEASURES

Total and age-group related major amputation rates, mortality, rates of arterial interventions, limb salvage rate.

MAIN RESULTS

The population > 65 years of age increased by 50% from 1970 to 1991. Major amputation rates increased 2.5 times from 1970 to 1981. The mean age at amputation increased from 71 to 78 years and at reconstruction from 68 to 74 years. The increase in numbers of reconstructions for CLI by 100% from 1980 onwards was associated with a reduction in amputation rate by 60% from 1983 to 1991. The 1- and 5-year survival rate after amputation was 55 and 20% and after reconstruction 83 and 45%. After reconstruction 1-, 3- and 5-year limb salvage rates were 83, 78 and 77% and limb salvage until death was 74%.

CONCLUSIONS

With an aggressive reconstruction policy in CLI it is possible to reduce amputation rates with a reasonable mortality and morbidity even in patients in the 8th and 9th decade of life.

摘要

目的

分析积极的血管重建策略对特定人群中严重下肢缺血结局的影响。

设计

对22年(1970 - 1991年)间研究区域内与人群数据相关的外科住院患者数据进行回顾性调查。

地点

芬兰西部的瓦萨中心医院区。该地区由一家中心医院和两家地区医院提供服务。

材料

研究开始时人口为165,000,结束时为178,000,其中977例因慢性严重下肢缺血(CLI)需要干预,397例因急性缺血,313例因非严重下肢缺血。

主要结局指标

总体及按年龄组划分的大截肢率、死亡率、动脉干预率、肢体挽救率。

主要结果

1970年至1991年间,65岁以上人群增加了50%。1970年至1981年间,大截肢率增加了2.5倍。截肢的平均年龄从71岁增加到78岁,重建的平均年龄从68岁增加到74岁。从1980年起,CLI重建数量增加了100%,这与1983年至1991年间截肢率降低60%相关。截肢后1年和5年生存率分别为55%和20%,重建后为83%和45%。重建后1年、3年和5年的肢体挽救率分别为83%、78%和77%,直至死亡的肢体挽救率为

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