Sequence of the gene encoding the N-terminal portion of the Plasmodium yoelii yoelii 17XL merozoite surface protein-1 (MSP-1).

The nucleotide (nt) sequence of the 5' portion of the gene encoding the Plasmodium yoelii yoelii (Pyy) 17XL merozite surface protein-1 (MSP-1) was determined by direct sequencing of both strands of the polymerase chain reaction (PCR) product. This report completes the entire coding region of the Pyy 17XL MSP-1 gene which we have found to be identical to the nt sequence of the Pyy YM MSP-1 [Lewis, Mol. Biochem. Parasitol. 36 (1989) 271-282], despite independent selection of parasite clones, passages and replications in mice over many years.