Grimshaw W T, Hunt K R, Hong C, Coles G C
Central Veterinary Laboratory, Weybridge, Surrey.
Vet Rec. 1994 Oct 15;135(16):372-4. doi: 10.1136/vr.135.16.372.
On five farms identified by in vitro tests to have benzimidazole resistance, and on one farm with apparent anthelmintic failure, faecal egg count reduction tests were performed using benzimidazoles, levamisole and ivermectin. With benzimidazoles efficacy was less than 70 per cent on all farms, confirming the validity of the in vitro tests to detect benzimidazole resistance. On two farms levamisole had an efficacy of less than 90 per cent but laboratory tests failed to demonstrate levamisole resistance. Ivermectin reduced egg counts by 100 per cent on all farms.
在通过体外试验确定存在苯并咪唑抗性的5个农场,以及在1个出现明显驱虫失败的农场,使用苯并咪唑、左旋咪唑和伊维菌素进行了粪便虫卵计数减少试验。使用苯并咪唑时,所有农场的疗效均低于70%,证实了体外试验检测苯并咪唑抗性的有效性。在2个农场,左旋咪唑的疗效低于90%,但实验室检测未能证明存在左旋咪唑抗性。伊维菌素在所有农场均使虫卵计数减少了100%。