Lysenko H I
Lik Sprava. 1994 May-Jun(5-6):21-5.
In this paper, low-molecular immunosuppressive lymphopeptide of molecular weight ranging from 300 to 500 daltons and anti-DNA autoantibodies have been shown to play a role in the formation of immunosuppression and development of secondary immunodeficiency states in patients with diffuse involvement of connective tissue, as evidenced by the analysis of the clinical and experimental studies. A concept of enzyme immunodeficiency in the pathogenesis of rheumatological diseases is documented. Special emphasis is put on the unsolved issues relative to this problem.
本文通过临床和实验研究分析表明，分子量在300至500道尔顿之间的低分子免疫抑制性淋巴细胞肽和抗DNA自身抗体在结缔组织广泛受累患者免疫抑制的形成及继发性免疫缺陷状态的发展中发挥作用。文献记载了酶免疫缺陷在风湿性疾病发病机制中的概念。特别强调了与该问题相关的未解决问题。
