Goertzen M, Ritsch M, Schulitz K P
Orthopädische Klinik und Poliklinik, Heinrich-Heine-Universität.
Z Orthop Ihre Grenzgeb. 1994 Nov-Dec;132(6):482-5. doi: 10.1055/s-2008-1039473.
Patients with beta-thalassemia develop a specific osteoarthropathy as they approach the second life decade. Radiological changes included osteopenia, widened medullary spaces, thin cortices with coarse reticulations, evidence of microfractures, premature epiphysiodesis of long bones and skeletal deformations. The fact that currently patients with beta-thalassemia have a longer life expectancy may explain the recent observations in this case report of this entity, which should become more familiar to orthopaedic surgeons who treat thalassemia patients in the future.
β地中海贫血患者在接近第二个十年生命期时会出现一种特定的骨关节炎。放射学改变包括骨质减少、骨髓腔增宽、皮质变薄伴粗大网纹、微骨折迹象、长骨过早骨骺闭合以及骨骼畸形。目前β地中海贫血患者预期寿命更长这一事实，或许可以解释本病例报告中对该病症的最新观察结果，未来治疗地中海贫血患者的骨科医生应该会对其更加熟悉。
