Shopotov I K, Fedin A N, Krivchenko A I, Vasil'eva O V
Zh Evol Biokhim Fiziol. 1993 Jul-Aug;29(4):352-7.
Different reactions were found in the cervical and thoracal parts of the trachea to application of acetylcholine, cholinomimetics and cholinolytics. The effect of acetylcholine on the cervical part is associated with muscarinic receptors in muscles. In the thoracal trachea, the effect of acetylcholine at a low concentration is associated mainly with muscle cholinoreceptors, whereas at high concentrations its effect is determined by both myogenic and neurogenic factors. Cholinergic systems of the intramural ganglia are involved in contraction and relaxation of tracheal smooth muscle in rats.
在气管的颈部和胸部对乙酰胆碱、拟胆碱药和抗胆碱药的应用发现了不同的反应。乙酰胆碱对颈部的作用与肌肉中的毒蕈碱受体有关。在胸段气管，低浓度乙酰胆碱的作用主要与肌肉胆碱能受体有关，而高浓度时其作用则由肌源性和神经源性因素共同决定。壁内神经节的胆碱能系统参与大鼠气管平滑肌的收缩和舒张。
