果蝇整合素及其配体。
Drosophila integrins and their ligands.
作者信息
Gotwals P J, Paine-Saunders S E, Stark K A, Hynes R O
机构信息
Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge 02139.
出版信息
Curr Opin Cell Biol. 1994 Oct;6(5):734-9. doi: 10.1016/0955-0674(94)90101-5.
PMID:7833052
Abstract
The major advance during the past year was the identification of ligands for two of the previously known position-specific integrins in Drosophila. At the same time, two new Drosophila integrin subunits (one alpha and one beta) were discovered, and significant progress was made on developmental genetic analyses of integrin functions, shedding light on the roles of integrins in Drosophila development.
摘要
过去一年的主要进展是确定了果蝇中两个先前已知的位置特异性整合素的配体。与此同时，发现了两个新的果蝇整合素亚基（一个α亚基和一个β亚基），并且在整合素功能的发育遗传学分析方面取得了重大进展，这为整合素在果蝇发育中的作用提供了线索。
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