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[电针对红霉素所致家兔胃肠电活动节律紊乱的调节作用]

[Regulating effect of electro-acupuncture on dysrythmia of gastro-colonic electric activity induced by erythromycine in rabbits].

作者信息

Xu G

机构信息

Institute of Acupuncture and Meridian, Anhui College of TCM, Hefei, China.

出版信息

Zhen Ci Yan Jiu. 1994;19(1):71-4.

PMID:7834859
Abstract

The myoelectric activity of gastro-colon was recorded in 20 rabbits. The model of gastro-colonic disorder was produced by vena injection of erythromycine (EM) (7 mg/kg). We investigated regulating effect of electro-acupuncture (EA) on the disorder of gastrocolonic electric activity (GEA). After the vagotomy the effect of EA was observed. In fasting and anaesthetic rabbits, the frequency and amplitude of GEA were 4.47 +/- 1.23 cmp, 1.90 +/- 0.27 mV at antrum, 8.33 +/- 2.61 cpm, 0.51 +/- 0.12 mV at ascending colon, 6.74 +/- 2.68 cpm, 0.35 +/- 0.10 mV at descending colon. After injection of EM, the frequency and amplitude of GEA were increased, the latency and duration of EM effect were 36.5 +/- 4.5 min and 3.8 +/- 1.4 min, the great contraction wave was showed. EA could shorten the duration and latency, decrease the frequency, amplitude and variation coefficient of GEA. After vagotomy the effect of EA disappeared. These results indicate that vagus nerve plays an important role in regulating effect of EA on gastro-colonic disorder.

摘要

记录了20只家兔的胃结肠肌电活动。通过静脉注射红霉素(EM)(7mg/kg)建立胃结肠功能紊乱模型。我们研究了电针(EA)对胃结肠电活动(GEA)紊乱的调节作用。切断迷走神经后观察EA的作用。在禁食和麻醉的家兔中,胃窦部GEA的频率和幅度分别为4.47±1.23次/分钟、1.90±0.27mV,升结肠为8.33±2.61次/分钟、0.51±0.12mV,降结肠为6.74±2.68次/分钟、0.35±0.10mV。注射EM后,GEA的频率和幅度增加,EM作用的潜伏期和持续时间分别为36.5±4.5分钟和3.8±1.4分钟,出现大的收缩波。EA可缩短持续时间和潜伏期,降低GEA的频率、幅度和变异系数。切断迷走神经后,EA的作用消失。这些结果表明迷走神经在EA对胃结肠紊乱的调节作用中起重要作用。

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